• en
  • cs

Dr. Xiaohui "Sophie" Ju
orc_id ORCID 0000-0002-4468-6003
researcher_id Researcher ID P-6206-2017
scopus_id Scopus ID 55568831100


Year 2022

  1. Purikova, O; Tkachenko, I; Šmíd, B; Veltruská, K; Dinhová, TN; Vorokhta, M; Kopecký, V; Hanyková, L; Ju, X
    Free‐Blockage Mesoporous Silica Nanoparticles Loaded with Cerium Oxide as ROS‐Responsive and ROS‐Scavenging Nanomedicine
    Adv. Funct. Mater. 32 (46) : Art. No. 2208316 (21 pages), 2022.
    doi:10.1002/adfm.202208316 (abstract link)  PDF ISI ID:000860643300001 BibTeX & \bibitem

Year 2021

  1. Ju, X; Šmíd, B; Johánek, V; Khalakhan, I; Yakovlev, Y; Matolínová, I; Matolín, V
    Investigation of dextran adsorption on polycrystalline cerium oxide surfaces
    Appl. Surf. Sci. 544 : Art. No. 148890 (11 pages), 2021.
    doi:10.1016/j.apsusc.2020.148890 (abstract link)  PDF ISI ID:000618292900006 BibTeX & \bibitem
  2. Ju, X; Hubalek Kalbacova, M; Šmíd, B; Johánek, V; Janata, M; Dinhová, TN; Bělinová, T; Mazur, M; Vorokhta, M; Strnad, L
    Poly(acrylic acid)-mediated synthesis of cerium oxide nanoparticles with variable oxidation states and their effect on regulating the intracellular ROS level
    J. Mater. Chem. B 9 (36) :  (15 pages), 2021.
    doi:10.1039/d1tb00706h (abstract link)  PDF ISI ID:000687271100001 BibTeX & \bibitem

Scientific activities

Dr. Ju’s current research is focused on the bio-application of cerium oxide nanoparticles (CeNPs) as future nanomedicine. Her scientific activities serve to answer the four questions regarding these CeNPs:

How to make them? CeNPs synthesis; CeNPs functionalization; design of CeNPs drug delivery systems.

What do they look like? CeNPs physicochemical characterization; CeNPs characterization in biological environments.

How do they interact with cells? CeNPs cellular uptake, distribution, and cytotoxicity.

How do they work in cells? CeNPs enzyme mimetic mechanism related to the Ce3+ and Ce4+ switch.


Scientific expertise

Chemical synthesis of CeNPs and their functionalization. Colloidal science of nanoparticles. Characterization such as UV-visible spectroscopy (UV-Vis), dynamic light scattering (DLS), and X-ray photoelectron spectroscopy (XPS) of biological materials and nanomaterials. Characterization of nanoparticle-cell interaction.