Home Surface Physics Laboratory – Hydrogen Technology Center People Dr. Xiaohui "Sophie" Ju

Dr. Xiaohui "Sophie" Ju

	juxiaohui9784@hotmail.com
	+420-95155-2337 +420-95155-2671
	Prague

	ORCID	0000-0002-4468-6003
	Researcher ID	P-6206-2017
	Scopus ID	55568831100

Publications

Year 2022

Purikova, O; Tkachenko, I; Šmíd, B; Veltruská, K; Dinhová, TN; Vorokhta, M; Kopecký, V; Hanyková, L; Ju, X
Free‐Blockage Mesoporous Silica Nanoparticles Loaded with Cerium Oxide as ROS‐Responsive and ROS‐Scavenging Nanomedicine
Adv. Funct. Mater. , 32 (46) : Art. No. 2208316 (21 pages), 2022.
doi:10.1002/adfm.202208316 (abstract link) | PDF | ISI ID:000860643300001 | BibTeX & \bibitem

Year 2021

Ju, X; Šmíd, B; Johánek, V; Khalakhan, I; Yakovlev, Y; Matolínová, I; Matolín, V
Investigation of dextran adsorption on polycrystalline cerium oxide surfaces
Appl. Surf. Sci. , 544 : Art. No. 148890 (11 pages), 2021.
doi:10.1016/j.apsusc.2020.148890 (abstract link) | PDF | ISI ID:000618292900006 | BibTeX & \bibitem
Ju, X; Hubalek Kalbacova, M; Šmíd, B; Johánek, V; Janata, M; Dinhová, TN; Bělinová, T; Mazur, M; Vorokhta, M; Strnad, L
Poly(acrylic acid)-mediated synthesis of cerium oxide nanoparticles with variable oxidation states and their effect on regulating the intracellular ROS level
J. Mater. Chem. B , 9 (36) : (15 pages), 2021.
doi:10.1039/d1tb00706h (abstract link) | PDF | ISI ID:000687271100001 | BibTeX & \bibitem

Scientific activities

Dr. Ju’s current research is focused on the bio-application of cerium oxide nanoparticles (CeNPs) as future nanomedicine. Her scientific activities serve to answer the four questions regarding these CeNPs:

How to make them? CeNPs synthesis; CeNPs functionalization; design of CeNPs drug delivery systems.

What do they look like? CeNPs physicochemical characterization; CeNPs characterization in biological environments.

How do they interact with cells? CeNPs cellular uptake, distribution, and cytotoxicity.

How do they work in cells? CeNPs enzyme mimetic mechanism related to the Ce³⁺ and Ce⁴⁺ switch.

Scientific expertise

Chemical synthesis of CeNPs and their functionalization. Colloidal science of nanoparticles. Characterization such as UV-visible spectroscopy (UV-Vis), dynamic light scattering (DLS), and X-ray photoelectron spectroscopy (XPS) of biological materials and nanomaterials. Characterization of nanoparticle-cell interaction.