Dr. Ju’s current research is focused on the bio-application of cerium oxide nanoparticles (CeNPs) as future nanomedicine. Her scientific activities serve to answer the four questions regarding these CeNPs:
How to make them? CeNPs synthesis; CeNPs functionalization; design of CeNPs drug delivery systems.
What do they look like? CeNPs physicochemical characterization; CeNPs characterization in biological environments.
How do they interact with cells? CeNPs cellular uptake, distribution, and cytotoxicity.
How do they work in cells? CeNPs enzyme mimetic mechanism related to the Ce3+ and Ce4+ switch.
Chemical synthesis of CeNPs and their functionalization. Colloidal science of nanoparticles. Characterization such as UV-visible spectroscopy (UV-Vis), dynamic light scattering (DLS), and X-ray photoelectron spectroscopy (XPS) of biological materials and nanomaterials. Characterization of nanoparticle-cell interaction.