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Dr. Xiaohui "Sophie" Ju

Researcher

juxiaohui9784@hotmail.com
+420-95155-2337
+420-95155-2671
Prague
orc_id ORCID 0000-0002-4468-6003
researcher_id Researcher ID P-6206-2017
scopus_id Scopus ID 55568831100
people

Publications

Year 2021

  1. Ju, X; Šmíd, B; Johánek, V; Khalakhan, I; Yakovlev, Y; Matolínová, I; Matolín, V
    Investigation of dextran adsorption on polycrystalline cerium oxide surfaces
    Appl. Surf. Sci. 544 : Art. No. 148890 (11 pages), 2021.
    doi:10.1016/j.apsusc.2020.148890 (abstract link)  PDF ISI ID:000618292900006 BibTeX & \bibitem

Year 2020

  1. Ju, X; Fučíková, A; Šmíd, B; Nováková, J; Matolínová, I; Matolín, V; Janata, M; Bělinová, T; Hubálek Kalbáčová, M
    Colloidal stability and catalytic activity of cerium oxide nanoparticles in cell culture media
    RSC Adv. 10 :  (12 pages), 2020.
    doi:10.1039/D0RA08063B (abstract link)  PDF ISI ID:000584324000003 BibTeX & \bibitem

Scientific activities

Dr. Ju’s current research is focused on the bio-application of cerium oxide nanoparticles (CeNPs) as future nanomedicine. Her scientific activities serve to answer the four questions regarding these CeNPs:

How to make them? CeNPs synthesis; CeNPs functionalization; design of CeNPs drug delivery systems.

What do they look like? CeNPs physicochemical characterization; CeNPs characterization in biological environments.

How do they interact with cells? CeNPs cellular uptake, distribution, and cytotoxicity.

How do they work in cells? CeNPs enzyme mimetic mechanism related to the Ce3+ and Ce4+ switch.

    

Scientific expertise

Chemical synthesis of CeNPs and their functionalization. Colloidal science of nanoparticles. Characterization such as UV-visible spectroscopy (UV-Vis), dynamic light scattering (DLS), and X-ray photoelectron spectroscopy (XPS) of biological materials and nanomaterials. Characterization of nanoparticle-cell interaction.